Lethal effect and apoptotic DNA fragmentation in response of D-GalN-treated mice to bacterial LPS can be suppressed by pre-exposure to minute amount of bacterial LPS: Dual role of TNF receptor 1

AIM: To investigate whether induction of tolerance of mice to lipopolysaccharide (LPS) was able to inhibit apoptotic reaction in terms of characteristic DNA fragmentation and protect mice from lethal effect. METHODS: Experimental groups of mice were pretreated with non-lethal amount of LPS (0.05 μg)...

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Bibliographische Detailangaben
Veröffentlicht in:World J Gastroenterol
Hauptverfasser: Zhou, Bing-Rong, Gumenscheimer, Marina, Freudenberg, Marina A., Galanos, Chris
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Inc 2005
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315994/
https://ncbi.nlm.nih.gov/pubmed/15948245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i22.3398
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