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P-glycoprotein is not involved in pathway of anti-Fas/Fas-induced apoptosis in KBv200 cells

AIM: To verify whether P-glycoprotein (P-gp) could induce cell resistance to apoptosis by inhibiting caspase-8 and caspase-3. METHODS: Human KB cells, either drug-sensitive or with multidrug resistance (MDR) phenotype caused by overexpression of P-gp (KBv200 cells), were treated with anti-Fas (CH-11...

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Bibliografski detalji
Izdano u:World J Gastroenterol
Glavni autori: Wu, Qiu-Liang, Wu, Xing-Ping, Liang, Yong-Ju, Chen, Li-Ming, Ding, Yan, Fu, Li-Wu
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315957/
https://ncbi.nlm.nih.gov/pubmed/15962371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i23.3544
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