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Definition and management of ruxolitinib treatment failure in myelofibrosis

Ruxolitinib, a Janus kinase (JAK)-1 and JAK-2 inhibitor, is the first-in-class drug to be licensed in the United States for the treatment of high- and intermediate-risk myelofibrosis (MF). Several other JAK inhibitors are in development with some currently undergoing phase-3 clinical trial testing....

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Pardanani, A, Tefferi, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315890/
https://ncbi.nlm.nih.gov/pubmed/25501025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2014.84
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