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Bioenergetics in clinical medicine: prevention by forms of coenzyme Q of the inhibition by adriamycin of coenzyme Q10-enzymes in mitochondria of the myocardium.

Adriamycin inhibits the succinoxidase system and the NADH-oxidase system. Both of the intact mitocondrial enzymes and the pentane-extracted preparations are inhibited. The inhibition can be prevented by a molar ratio of coenzyme to adriamycin of 3:1 for coenzyme Q10 (ubiquinone), 5:1 for coenzyme Q7...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Kishi, T, Watanabe, T, Folkers, K
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1976
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431583/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1070015/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.12.4653
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