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Effects of colchicine on cyclic AMP levels in human leukocytes

The increase in human leukocyte adenosine 3′:5′-cyclic monophosphate (cyclic AMP) levels seen in response to various substances was markedly potentiated by colchicine and other agents that affect microtubule assembly. Addition of dl-isoproterenol (2 μM) or prostaglandin E(1) (10 μM), together with t...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Rudolph, Stephen A., Greengard, Paul, Malawista, Stephen E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1977
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431582/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/198784/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.8.3404
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