Increased expression of IL-18 in the serum and islets of type 1 diabetics

Type 1 diabetes (T1D) is a chronic disease characterized by autoimmune-mediated destruction of pancreatic insulin-producing beta cells. Interleukin (IL)-18 is a pro-inflammatory cytokine implicated in the pathogenesis of a number of inflammatory diseases. Here, we analyzed IL-18 levels in the plasma...

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Veröffentlicht in:Mol Immunol
Hauptverfasser: Harms, Robert Z., Yarde, Danielle N., Guinn, Zachary, Lorenzo-Arteaga, Kristina M., Corley, Kevin P., Cabrera, Monina S., Sarvetnick, Nora E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315765/
https://ncbi.nlm.nih.gov/pubmed/25576800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.12.012
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