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Association of CD33 Polymorphism rs3865444 with Alzheimer’s Disease Pathology and CD33 Expression in Human Cerebral Cortex

Recent findings identified the minor A allele present in the single nucleotide polymorphism rs3865444 in the CD33 gene as being associated with reduced risk of developing Alzheimer’s disease (AD). CD33 (Siglec-3) is an immune function protein with anti-inflammatory signaling, cell adhesion and endoc...

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Bibliographische Detailangaben
Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Walker, Douglas G., Whetzel, Alexis, Serrano, Geidy, Sue, Lucia I, Beach, Thomas G., Lue, Lih-Fen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315751/
https://ncbi.nlm.nih.gov/pubmed/25448602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.09.023
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