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Mammalian target of Rapamycin Complex 2 Regulates Invariant Natural Killer T Cell Development and Function Independent of Promyelocytic Leukemia Zinc-finger

The mammalian target of rapamycin (mTOR) senses and incorporates different environmental cues via the two signaling complexes mTORC1 and mTORC2. As a result, mTOR controls cell growth and survival and also shapes different effector functions of the cells including immune cells such as T cells. We de...

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Foilsithe in:J Immunol
Main Authors: Prevot, Nicolas, Pyaram, Kalyani, Bischoff, Evan, Sen, Jyoti Misra, Powell, Jonathan D, Chang, Cheong-Hee
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315517/
https://ncbi.nlm.nih.gov/pubmed/25404366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401985
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