MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis

PURPOSE: The aim of this study was to find clinically relevant MIBG-avid metastatic patterns in patients with newly diagnosed stage 4 neuroblastoma. METHODS: Diagnostic (123)I-MIBG scans from 249 patients (123 from a European and 126 from the COG cohort) were assessed for metastatic spread in 14 bod...

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Detalhes bibliográficos
Publicado no:Eur J Nucl Med Mol Imaging
Main Authors: Bleeker, Gitta, van Eck-Smit, Berthe L., Zwinderman, Koos H., Versteeg, Rogier, van Noesel, Max M., Kam, Boen L., Kaspers, Gertjan J., van Schie, Annelies, Kreissman, Susan G., Yanik, Gregory, Hero, Barbara, Schmidt, Matthias, Laureys, Geneviève, Lambert, Bieke, Øra, Ingrid, Schulte, Johannes H., Caron, Huib N., Tytgat, Godelieve A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315489/
https://ncbi.nlm.nih.gov/pubmed/25267348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-014-2909-1
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