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The genetics of familial hypercholesterolemia and emerging therapies

Familial hypercholesterolemia (FH) results in very high levels of atherogenic low-density lipoprotein (LDL) cholesterol from the time of birth. Mutations of the genes encoding for the LDL receptor, apolipoprotein B and proprotein convertase subtilisin/kexin type 9, are causes for this autosomal domi...

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Sparad:
Bibliografiska uppgifter
I publikationen:Appl Clin Genet
Huvudupphovsman: Vogt, Anja
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315461/
https://ncbi.nlm.nih.gov/pubmed/25670911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S44315
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