Signatures of Natural Selection at the FTO (Fat Mass and Obesity Associated) Locus in Human Populations

BACKGROUND AND AIMS: Polymorphisms in the first intron of FTO have been robustly replicated for associations with obesity. In the Sorbs, a Slavic population resident in Germany, the strongest effect on body mass index (BMI) was found for a variant in the third intron of FTO (rs17818902). Since this...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Xuanshi, Weidle, Kerstin, Schröck, Kristin, Tönjes, Anke, Schleinitz, Dorit, Breitfeld, Jana, Stumvoll, Michael, Böttcher, Yvonne, Schöneberg, Torsten, Kovacs, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315420/
https://ncbi.nlm.nih.gov/pubmed/25647475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117093
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