Distinct serum metabolomics profiles associated with malignant progression in the Kras(G12D) mouse model of pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer deaths worldwide with less than a 6% 5-year survival rate. PDAC is associated with poor prognosis based on the late stage diagnosis of the disease. Current diagnostic tests lack the sensitivity and specificity...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: LaConti, Joseph J, Laiakis, Evagelia C, Mays, Anne Deslattes, Peran, Ivana, Kim, Sung Eun, Shay, Jerry W, Riegel, Anna T, Fornace, Albert J, Wellstein, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315147/
https://ncbi.nlm.nih.gov/pubmed/25923219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S1-S1
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