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A use-dependent increase in release sites drives facilitation at calretinin-deficient cerebellar parallel-fiber synapses

Endogenous Ca(2+)-binding proteins affect synaptic transmitter release and short-term plasticity (STP) by buffering presynaptic Ca(2+) signals. At parallel-fiber (PF)-to-Purkinje neuron (PN) synapses in the cerebellar cortex loss of calretinin (CR), the major buffer at PF terminals, results in incre...

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Foilsithe in:Front Cell Neurosci
Main Authors: Brachtendorf, Simone, Eilers, Jens, Schmidt, Hartmut
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315043/
https://ncbi.nlm.nih.gov/pubmed/25691858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00027
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