BRAF mutation is associated with a specific cell-type with features suggestive of senescence in ovarian serous borderline (atypical proliferative) tumors

Serous borderline tumor (SBT) also known as atypical proliferative serous tumor (APST) is the precursor of ovarian low-grade serous carcinoma (LGSC). In this study, we correlated the morphologic and immunohistochemical phenotypes of 71 APSTs and 18 LGSCs with the mutational status of KRAS and BRAF,...

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Detalhes bibliográficos
Publicado no:Am J Surg Pathol
Main Authors: Zeppernick, Felix, Ardighieri, Laura, Hannibal, Charlotte G., Vang, Russell, Junge, Jette, Kjaer, Susanne K., Zhang, Rugang, Kurman, Robert J., Shih, Ie-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314953/
https://ncbi.nlm.nih.gov/pubmed/25188864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000313
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