Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy

BACKGROUND: The poor response to chemotherapy and the brief response to vemurafenib in metastatic melanoma patients, make the identification of new therapeutic approaches an urgent need. Interestingly the increased expression and activity of the Aurora kinase B during melanoma progression suggests i...

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Gepubliceerd in:J Transl Med
Hoofdauteurs: Porcelli, Letizia, Guida, Gabriella, Quatrale, Anna E, Cocco, Tiziana, Sidella, Letizia, Maida, Immacolata, Iacobazzi, Rosa M, Ferretta, Anna, Stolfa, Diana A, Strippoli, Sabino, Guida, Stefania, Tommasi, Stefania, Guida, Michele, Azzariti, Amalia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314759/
https://ncbi.nlm.nih.gov/pubmed/25623468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0385-4
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