Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1β

BACKGROUND: Galectin-3 (gal-3), a member of the β-galactoside-binding animal lectins, is involved in the recruitment, activation and removal of neutrophils. Neutrophilic asthma is characterized by a persistent elevation of airway neutrophils and impaired efferocytosis. We hypothesized that sputum ga...

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Bibliographic Details
Published in:	Respir Res
Main Authors:	Gao, Peng, Gibson, Peter G, Baines, Katherine J, Yang, Ian A, Upham, John W, Reynolds, Paul N, Hodge, Sandra, James, Alan L, Jenkins, Christine, Peters, Matthew J, Zhang, Jie, Simpson, Jodie L
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2015
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4314745/ https://ncbi.nlm.nih.gov/pubmed/25616863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0163-5
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Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1β

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