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Mechanisms of Gefitinib-mediated reversal of tamoxifen resistance in MCF-7 breast cancer cells by inducing ERα re-expression

Estrogen receptor (ER)-positive breast cancer patients may turn ER-negative and develop acquired drug resistance, which compromises the efficacy of endocrine therapy. By investigating the phenomenon that gefitinib can re-sensitise tamoxifen (TAM)-resistant MCF-7 breast cancer cells (MCF-7/TAM) to TA...

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Bibliografske podrobnosti
izdano v:	Sci Rep
Main Authors:	Zhang, Xia, Zhang, Bin, Liu, Jie, Liu, Jiwei, Li, Changzheng, Dong, Wei, Fang, Shu, Li, Minmin, Song, Bao, Tang, Bo, Wang, Zhehai, Zhang, Yang
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2015
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4314651/ https://ncbi.nlm.nih.gov/pubmed/25644501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07835
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Mechanisms of Gefitinib-mediated reversal of tamoxifen resistance in MCF-7 breast cancer cells by inducing ERα re-expression

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