In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus.

Acetylcholine receptor (AChR) genes are repressed in extrajunctional domains of adult muscle fiber by neurally evoked electrical activity. Denervation elicits upregulation of AChR gene transcription in extrasynaptic areas. We have used an adenovirus (Ad)-based strategy to analyze in vitro and in viv...

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Bibliographic Details
Main Authors: Bessereau, J L, Stratford-Perricaudet, L D, Piette, J, Le Poupon, C, Changeux, J P
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC43146/
https://ncbi.nlm.nih.gov/pubmed/8108406
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