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Central insulin signaling modulates hypothalamus–pituitary–adrenal axis responsiveness

OBJECTIVE: Obesity is often accompanied by hyperactivity of the neuroendocrine stress axis and has been linked to an increased risk of psychiatric disorders. Insulin is reciprocally regulated with the stress hormone corticosterone (CORT), raising the possibility that insulin normally provides inhibi...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Chong, Angie C.N., Vogt, Merly C., Hill, Alexis S., Brüning, Jens C., Zeltser, Lori M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314547/
https://ncbi.nlm.nih.gov/pubmed/25685696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.12.001
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