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Invariant tryptophan at a shielded site promotes folding of the conformational unit of spectrin.

The tryptophan that is highly conserved among repeating structural units of spectrin is reported to promote the conformational stability of one such unit of chicken brain alpha-spectrin. Four constructs were inserted into pET vectors for overexpression in Escherichia coli of the following spectrin p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: MacDonald, R I, Musacchio, A, Holmgren, R A, Saraste, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43145/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8108405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1299
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