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Imaging of mitochondrial Ca(2+) dynamics in astrocytes using cell-specific mitochondria-targeted GCaMP5G/6s: Mitochondrial Ca(2+) uptake and cytosolic Ca(2+) availability via the endoplasmic reticulum store
Mitochondrial Ca(2+) plays a critical physiological role in cellular energy metabolism and signaling, and its overload contributes to various pathological conditions including neuronal apoptotic death in neurological diseases. Live cell mitochondrial Ca(2+) imaging is an important approach to unders...
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Publié dans: | Cell Calcium |
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Auteurs principaux: | , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2014
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4314419/ https://ncbi.nlm.nih.gov/pubmed/25443655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2014.09.008 |
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