Imaging of mitochondrial Ca(2+) dynamics in astrocytes using cell-specific mitochondria-targeted GCaMP5G/6s: Mitochondrial Ca(2+) uptake and cytosolic Ca(2+) availability via the endoplasmic reticulum store

Mitochondrial Ca(2+) plays a critical physiological role in cellular energy metabolism and signaling, and its overload contributes to various pathological conditions including neuronal apoptotic death in neurological diseases. Live cell mitochondrial Ca(2+) imaging is an important approach to unders...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Calcium
Main Authors: Li, Hailong, Wang, Xiaowan, Zhang, Nannan, Gottipati, Manoj K., Parpura, Vladimir, Ding, Shinghua
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314419/
https://ncbi.nlm.nih.gov/pubmed/25443655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2014.09.008
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