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An APRT mutation is strongly associated with and likely causative for 2,8-dihydroxyadenine urolithiasis in dogs()

2,8-Dihydroxyadenine (2,8-DHA) urolithiasis in people is caused by autosomal recessive mutations in the adenine phosphoribosyltransferase gene (APRT). 2,8-DHA urolithiasis has recently been reported in two dogs, but, to the authors’ knowledge, no studies have yet investigated the genetic basis for s...

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Détails bibliographiques
Publié dans:Mol Genet Metab
Auteurs principaux: Furrow, Eva, Pfeifer, Randall J., Osborne, Carl A., Lulich, Jody P.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314209/
https://ncbi.nlm.nih.gov/pubmed/24359665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2013.12.002
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