TRPM4 inhibitor 9-phenanthrol activates endothelial cell intermediate conductance calcium-activated potassium channels in rat isolated mesenteric artery

BACKGROUND AND PURPOSE: Smooth muscle transient receptor potential melastatin 4 (TRPM4) channels play a fundamental role in the development of the myogenic arterial constriction that is necessary for blood flow autoregulation. As TRPM4 channels are present throughout the vasculature, we investigated...

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Publicat a:Br J Pharmacol
Autors principals: Garland, C J, Smirnov, S V, Bagher, P, Lim, C S, Huang, C Y, Mitchell, R, Stanley, C, Pinkney, A, Dora, K A
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314199/
https://ncbi.nlm.nih.gov/pubmed/25323322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12985
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