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Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota

BACKGROUND AND PURPOSE: Hydrogen sulphide is an important mediator of gastrointestinal mucosal defence. The use of non-steroidal anti-inflammatory drugs (NSAIDs) is significantly limited by their toxicity in the gastrointestinal tract. Particularly concerning is the lack of effective preventative or...

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Publicado en:Br J Pharmacol
Autores principales: Blackler, Rory W, Motta, Jean-Paul, Manko, Anna, Workentine, Matthew, Bercik, Premysl, Surette, Michael G, Wallace, John L
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314190/
https://ncbi.nlm.nih.gov/pubmed/25297699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12961
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