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The opiate receptor: a model explaining structure-activity relationships of opiate agonists and antagonists.

A model of the opiate receptor is proposed which explains structure-activity relationships of opiate drugs, including (i) the unique potency of certain opiates such as etonitazene, fentanyl, phenazocine, and oripavines; (ii) the role of N-allyl substituents in conferring antagonist properties; and (...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Feinberg, A P, Creese, I, Snyder, S H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431391/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/186791/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.11.4215
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