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Total Synthesis of Calothrixins A and B via Oxidative Radical Reaction of Cyclohexenone with Aminophenanthridinedione

Bioactive indolo[3,2-j]phenanthridine alkaloids, calothrixin B and its N-oxide derivative calothrixin A have been synthesized via an oxidative free radical reaction. calothrixin B is generated from the commercially available 2,4,5-trimethoxybenzaldehyde in only 7 steps. The key step in this synthesi...

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Bibliografiske detaljer
Udgivet i:Tetrahedron
Main Authors: Xu, Su, Nguyen, Thao, Pomilio, Irene, Vitale, Maria C., Velu, Sadanandan E.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313744/
https://ncbi.nlm.nih.gov/pubmed/25663720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2014.06.021
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