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Thinking outside the box about COX-1 in Alzheimer's disease
This article from Coma et al. shows that a salicylic acid derivative Triflusal, a platelet aggregation inhibitor and irreversible inhibitor of COX-1, can correct defects in axonal curvature and cognition in an AD transgenic mouse model (Tg2576) (Coma et al., 2010). Here we discuss the controversy ov...
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| Publicat a: | Neurobiol Dis |
|---|---|
| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4313739/ https://ncbi.nlm.nih.gov/pubmed/20206264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.02.009 |
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