Detection of Impaired IgG Antibody Formation Facilitates the Decision on Early Immunoglobulin Replacement in Hypogammaglobulinemic Patients

Hypogammaglobulinemia (serum IgG lower than 2 SD below the age-matched mean) and clinical symptoms such as increased susceptibility to infection, autoimmune manifestations, granulomatous disease, and unexplained polyclonal lymphoproliferation are considered to be diagnostic hallmarks in patients wit...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Wolf, Hermann M., Thon, Vojtech, Litzman, Jiri, Eibl, Martha M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313720/
https://ncbi.nlm.nih.gov/pubmed/25699049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00032
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