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Dopamine induces the accumulation of insoluble prion protein and affects autophagic flux

Accumulation of protein aggregates is a histopathological hallmark of several neurodegenerative diseases, but in most cases the aggregation occurs without defined mutations or clinical histories, suggesting that certain endogenous metabolites can promote aggregation of specific proteins. One example...

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Bibliografische gegevens
Gepubliceerd in:Front Cell Neurosci
Hoofdauteurs: da Luz, Marcio H. M., Peres, Italo T., Santos, Tiago G., Martins, Vilma R., Icimoto, Marcelo Y., Lee, Kil S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313710/
https://ncbi.nlm.nih.gov/pubmed/25698927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00012
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