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Development and Validation of a Sensitive and Specific sodB-Based Quantitative PCR Assay for Molecular Detection of Ehrlichia Species

We developed a sensitive and specific sodB-based quantitative PCR assay to detect Ehrlichia spp. The assay's limit of detection was 5 copies/reaction, and it did not amplify nonspecific DNA. Compared with a 16S rRNA gene PCR target, the sodB target may offer an improved molecular diagnostic ass...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Qurollo, Barbara A., Riggins, Dana, Comyn, Alaire, Zewde, Merone T., Breitschwerdt, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313244/
https://ncbi.nlm.nih.gov/pubmed/25143580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02340-14
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