Microevolution of Burkholderia pseudomallei during an Acute Infection

We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with acute disseminated melioidosis. Fourteen closely related genotypes were found, providing evidence for the rapid in vivo diversification of B. pseudomallei...

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Bibliografiske detaljer
Udgivet i:J Clin Microbiol
Main Authors: Limmathurotsakul, Direk, Holden, Matthew T. G., Coupland, Paul, Price, Erin P., Chantratita, Narisara, Wuthiekanun, Vanaporn, Amornchai, Premjit, Parkhill, Julian, Peacock, Sharon J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Bacteriology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313173/
https://ncbi.nlm.nih.gov/pubmed/24966357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01219-14
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