DNA methylation profiling of medulloblastoma allows robust sub-classification and improved outcome prediction using formalin-fixed biopsies

Molecular sub-classification is rapidly informing the clinical management of medulloblastoma. However, the disease remains associated with poor outcomes and therapy-associated late-effects, and the majority of patients are not characterized by a validated prognostic biomarker. Here, we investigated...

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Библиографические подробности
Опубликовано в: :Acta Neuropathol
Главные авторы: Schwalbe, Edward C., Williamson, Daniel, Lindsey, Janet C., Hamilton, Dolores, Ryan, Sarra L., Megahed, Hisham, Garami, Miklos, Hauser, Peter, Dembowska-Baginska, Bozena, Perek, Danuta, Northcott, Paul A., Taylor, Michael D., Taylor, Roger E., Ellison, David W., Bailey, Simon, Clifford, Steven C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313078/
https://ncbi.nlm.nih.gov/pubmed/23291781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1077-2
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