Tetrahydrobiopterin lowers muscle sympathetic nerve activity and improves augmentation index in patients with chronic kidney disease

Chronic kidney disease (CKD) is characterized by overactivation of the sympathetic nervous system (SNS) that contributes to cardiovascular risk. Decreased nitric oxide (NO) bioavailability is a major factor contributing to SNS overactivity in CKD, since reduced neuronal NO leads to increased central...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Park, Jeanie, Liao, Peizhou, Sher, Salman, Lyles, Robert H., Deveaux, Don D., Quyyumi, Arshed A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Neural Control
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313073/
https://ncbi.nlm.nih.gov/pubmed/25477424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00409.2014
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