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Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells

Dysregulated autophagy and decreased AMP-activated protein kinase (AMPK) activity are each associated with atherogenesis. Atherogenesis is preceded by high circulating concentrations of glucose and fatty acids, yet the mechanism by which these nutrients regulate autophagy in human aortic endothelial...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Weikel, Karen A., Cacicedo, José M., Ruderman, Neil B., Ido, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312840/
https://ncbi.nlm.nih.gov/pubmed/25354528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00265.2014
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