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Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunities
Excess iron is tightly associated with tumorigenesis in multiple human cancer types through a variety of mechanisms including catalyzing the formation of mutagenic hydroxyl radicals, regulating DNA replication, repair and cell cycle progression, affecting signal transduction in cancer cells, and act...
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| Publicado no: | Protein Cell |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312762/ https://ncbi.nlm.nih.gov/pubmed/25476483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-014-0119-z |
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