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Interneurons are necessary for coordinated activity during reversal learning in orbitofrontal cortex

BACKGROUND: Cerebral cortical GABAergic interneuron dysfunction is hypothesized to lead to cognitive deficits co-morbid with human neuropsychiatric disorders, including schizophrenia, autism and epilepsy. We have previously shown that mice that harbor mutations in the Plaur gene, which is associated...

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Bibliographic Details
Published in:Biol Psychiatry
Main Authors: Bissonette, Gregory B, Schoenbaum, Geoffrey, Roesch, Matthew R, Powell, Elizabeth M
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312743/
https://ncbi.nlm.nih.gov/pubmed/25193243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.07.023
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