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Reprogramming the genome to totipotency in mouse embryos
Despite investigative interest, the artificial derivation of pluripotent stem cells remains inefficient and incomplete reprogramming hinders its potential as a reliable tool in regenerative medicine. By contrast, fusion of terminally differentiated gametes at fertilization activates efficient epigen...
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| Publicado no: | Trends Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312727/ https://ncbi.nlm.nih.gov/pubmed/25448353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.09.006 |
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