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The initiation of synaptic 2-AG mobilization requires both an increased supply of diacylglycerol precursor and increased postsynaptic calcium

On-demand postsynaptic synthesis and release of endocannabinoid lipids and subsequent binding to presynaptic CB1 receptors (CB1Rs) mediates short and long-term depression (LTD) of excitatory transmission in many brain regions. However, mechanisms involved in the synthesis of the endocannabinoid 2-ar...

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Detaylı Bibliyografya
Yayımlandı:Neuropharmacology
Asıl Yazarlar: Shonesy, Brian C., Winder, Danny G., Patel, Sachin, Colbran, Roger J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312705/
https://ncbi.nlm.nih.gov/pubmed/25484252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.11.026
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