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Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts
Development of chromosomal instability (CIN) and consequent phenotypic heterogeneity represent common events during breast cancer progression. Breast carcinomas harboring extensive chromosomal aberrations display a more aggressive behavior characterized by chemoresistance and the propensity to give...
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Publicado en: | Int J Oncol |
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Autores principales: | , , , , , , , , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312700/ https://ncbi.nlm.nih.gov/pubmed/20878064 |
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