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Hydrolysis and transpeptidation of peptide substrates by acetyl-pepsin.

Treatment of swine pepsin with acetylimidazole to acetylate approximately five of its 16 tyrosyl residues causes a significant enhancement of catalytic efficiency (kcat/Km) toward substrates such as dansyl-glycyl-glycyl-L-phenylalanyl-L-phenylalanine 3-(4-pyridyl)propyl ester and benzyloxy-carbonyl-...

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Detalhes bibliográficos
Main Authors: Richman, P G, Fruton, J S
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC431264/
https://ncbi.nlm.nih.gov/pubmed/792877
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