Splice-Correction Strategies for Treatment of X-Linked Agammaglobulinemia

X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disease caused by mutations in the gene coding for Bruton’s tyrosine kinase (BTK). Deficiency of BTK leads to a developmental block in B cell differentiation; hence, the patients essentially lack antibody-producing plasma cells and are...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Curr Allergy Asthma Rep
Päätekijät: Bestas, Burcu, Turunen, Janne J., Blomberg, K. Emelie M., Wang, Qing, Månsson, Robert, EL Andaloussi, Samir, Berglöf, Anna, Smith, C. I. Edvard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2015
Aiheet:
Immune Deficiency and Dysregulation (DP Huston, Section Editor)
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312560/
https://ncbi.nlm.nih.gov/pubmed/25638286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11882-014-0510-0
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