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Splice-Correction Strategies for Treatment of X-Linked Agammaglobulinemia
X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disease caused by mutations in the gene coding for Bruton’s tyrosine kinase (BTK). Deficiency of BTK leads to a developmental block in B cell differentiation; hence, the patients essentially lack antibody-producing plasma cells and are...
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| Udgivet i: | Curr Allergy Asthma Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312560/ https://ncbi.nlm.nih.gov/pubmed/25638286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11882-014-0510-0 |
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