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Biotinylinsulins as potential tools for receptor studies

The preparation of affinity columns that contain insulin attached to Sepharose in a targeted manner by way of biotin-avidin noncovalent bonds is described. Insulin was acylated selectively at the amino terminus of the B chain with the N-hydroxysuccinimido ester of biotin to form N(α,B(1))-biotinylin...

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Detalhes bibliográficos
Main Authors: Hofmann, Klaus, Finn, Frances M., Friesen, Heinz-Jürgen, Diaconescu, Cornelia, Zahn, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC431250/
https://ncbi.nlm.nih.gov/pubmed/268619
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