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Dose-dependent depletion of nuclear receptors by L-triiodothyronine: evidence for a role in induction of growth hormone synthesis in cultured GH1 cells.

The relationship between the binding of L-triiodothyronine (T3) to nuclear receptors and the induction of growth hormone synthesis was examined in cultured GH1 cells, a rat pituitary cell line. After 24 hr, T3 induced a maximal 4-fold increase in the rate of growth hormone wynthesis; the T3 concentr...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Samuels, H H, Stanley, F, Shapiro, L E
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1976
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431249/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/186776/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.11.3877
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