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Bacterial CagA protein induces degradation of p53 protein in a p14ARF-dependent manner

OBJECTIVE: Infection with Helicobacter pylori is the strongest known risk factor for adenocarcinoma of the stomach. Tumorigenic transformation of gastric epithelium induced by H. pylori is a highly complex process driven by an active interplay between bacterial virulence and host factors, many aspec...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Wei, Jinxiong, Noto, Jennifer M, Zaika, Elena, Romero-Gallo, Judith, Piazuelo, Maria Blanca, Schneider, Barbara, El-Rifai, Wael, Correa, Pelayo, Peek, Richard M, Zaika, Alexander I
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312278/
https://ncbi.nlm.nih.gov/pubmed/25080447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307295
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