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Missing-in-Metastasis regulates cell motility and invasion via PTPδ-mediated changes in SRC activity

Missing in Metastasis (MIM), also known as MTSS1, is a scaffold protein that is down-regulated in multiple metastatic cancer cell lines compared to non-metastatic counterparts. MIM regulates cytoskeletal dynamics and actin polymerization, and has been implicated in the control of cell motility and i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochem J
Hauptverfasser: Chaudhary, Fauzia, Lucito, Robert, Tonks, Nicholas K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312213/
https://ncbi.nlm.nih.gov/pubmed/25287652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140573
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