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Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.

A high-molecular-weight DNA from Balb/c mouse early embryo or from MOPC 321 plasmacytoma (a k-chain producer) was digested to completion with Bacillus amyloliquefaciens strain H restriction enzyme (BamH I). The resulting DNA fragments were fractionated according to size in preparative agarose gel el...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hozumi, N, Tonegawa, S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431171/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/824647/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.10.3628
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