MRM-DIFF: data processing strategy for differential analysis in large scale MRM-based lipidomics studies

Based on theoretically calculated comprehensive lipid libraries, in lipidomics as many as 1000 multiple reaction monitoring (MRM) transitions can be monitored for each single run. On the other hand, lipid analysis from each MRM chromatogram requires tremendous manual efforts to identify and quantify...

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Detalhes bibliográficos
Publicado no:Front Genet
Principais autores: Tsugawa, Hiroshi, Ohta, Erika, Izumi, Yoshihiro, Ogiwara, Atsushi, Yukihira, Daichi, Bamba, Takeshi, Fukusaki, Eiichiro, Arita, Masanori
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311682/
https://ncbi.nlm.nih.gov/pubmed/25688256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00471
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