Very Short-Term Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin on the Secretion of Insulin, Glucagon, and Incretin Hormones in Japanese Patients with Type 2 Diabetes Mellitus: Analysis of Meal Tolerance Test Data

BACKGROUND: Sitagliptin inhibits dipeptidyl peptidase-4, which inactivates the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide. To assess its antidiabetic potency, we used meal tolerance tests (MTTs) to determine the very short-term effects of sitag...

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Udgivet i:Drugs R D
Main Authors: Murai, Kazuki, Katsuno, Tomoyuki, Miyagawa, Jun-ichiro, Matsuo, Toshihiro, Ochi, Fumihiro, Tokuda, Masaru, Kusunoki, Yoshiki, Miuchi, Masayuki, Namba, Mitsuyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2014
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311653/
https://ncbi.nlm.nih.gov/pubmed/25420579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-014-0072-6
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