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Kinetic evidence for hapten-induced conformational transition in immunoglobin MOPC 460.

The kinetics of hapten binding to the homogeneous immunoglobulin A secreted by the murine plasmacytoma MOPC 460 was investigated by the chemical relaxation method. Two distinct relaxation times were observed in the binding equilibrium with three different haptens. A detailed concentration dependence...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Lancet, D, Pecht, I
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431154/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1068466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.10.3549
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